Aezian

FILLER & CANNULA

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Filler & Cannula

re:on FILLER

- GLOBAL

- DEEP

- ULTRA

Cross-linked Hyaluronic acid dermal filler. Indication: Wrinkle treatment, Volumizing effect. 3 different ranges: Global, Deep, Ultra.

Characteristics

Non-animal origin

Hyaluronic acid from Streptococcus equi fermentation

Biocompatibility - Non-toxic / Non-immunogenic

Biodegradability
BDDE Cross-linked HA

BDDE cross-linked HA - Biphasic gel
High viscoelastic gel

HA Concentration : 20 mg/ml (2%)

High viscosity

Low injection force

General identity of re:on

Residual BDDE

Confirmed amount of residual BDDE in re:on through GC analysis. (Detection limit of BDDE: ≤2 ppm)
Protein Load

Protein load : Y product V < R product < Y product C < C product < re:on filler By reducing the amount of protein causing hypersensitivity reaction, it minimizes generation of free radical. Protein load of re:on filler is lower than other commercial products.
Endotoxin

Less than 5.0 EU/ml

Comparison of other filler vs re:on filler

From the internal duration test using mouse, re:on had longer durability than J-product and similar durability with R-product. From the histological test, re:on showed superior result within the material remaining for 4 months and connective tissues. (Plastic surgery division of Korea University Medical college -April, 2010)

Degree of cross-linking

(HA filler parameter)
Duration

(Clinical performance)

Manufacturing process

Hyaluronic acid (HA)
BDDE cross-linked HA

The half-life of natural HA administered in the body is very short, so it has to be modified in order to increase the stability in vivo.
Different median particle sizes