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aesPlla®

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PLLA Filler (Poly L-Lactic Acid Powder)
Safe & Durable collagen stimulator

CONTENTS: 365 mg x 1 vial (5ml)

TREATMENT AREA: Facial wrinkles and folds

PURPOSE OF USAGE: aesPlla® is indicated for use in immune-competent people as a single regimen for correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles in which deep dermal

aesPlla® is a Poly L-Lactic Acid based injectable dermal filler. This filler has been developed to fill the lost volume with stimulating collagenesis. The main ingredient of aesPlla® PLLA, has been used for more than 20 years in medical devices, including dissolvable stitches. Since aesPlla® is comprised of synthetic materials, there is no need for allergy testing prior to treatment.

What is aesPlla®?

Natural Volume with Longevity

Injected AesPlla PLLA Filler restores volume through stimulation collagen in the skin layer.
Generated bolume with own collagen lasts more than 2 years.

For Doctor

Convenient
Long lasting volume
Safe

Confirmed by Korean MFDS and achieved CE.
The main ingrerdient PLLA is biodegradable.
Economic

Solution = aesPlla® + WFI(Water For Injection) + Lidocaine
Steady treatment over 20 years

The treament for improving wrinkle with PLLA is being done over 20 years.
Short treatment time

For Patients

Natural result

The result will be shown gradually.
Long lasting volume
Quick recovery time

With less downtime, easy to return to daily life
Economic

Less costs less than other surgical treatments.
Volume Improvemnt & Restoration

Improvement Wrinkle improvement through collagen regeneration
Short treatment time

Mechanism of action

STEP 01

Inject diluted aesPlla® into the subcutaneous layer of the skin.
STEP 02

Fistly wrinkle improvment can be shown with WFI(Water for injection) and diluted aesPlla®.
STEP 03

Within a few days, after absorbing water, only the AesPlla PLLA particles remain
STEP 04

New cells are gathered around PLLA and increasing fibroblasts.
STEP 05

Increased fibroblasts stimulate collagen generation and improve skin folds.
STEP 06

Generated collagen lasts for 2 years and aesPlla® particled are biodegraded.

Superior Collagen stimulator PLLA

Therefore, compared with PDLA MS and PDLLA MS, PLLA MS is a skin filling material with lower cost, lower side reaction, better filling effect and excellent collagen stimulating effect.
Furthermore, PLLA MS can contain collagen and other substances that are benefical to skin repair and collagen regeneration, which anc be released slowly through PLLA degradation to achieve better cosmetic effect In brief, PLLA MA is a valuable and superior dermal filler.

Control
PDLA MS
PLLA MS
PDLLA MS

Collagen fiber, mucus and cartilage : Blue

Control
PDLA MS
PLLA MS
PDLLA MS

Type 1 collagen : Red or YellowType 3 collagen : Green

Histological analysis of collagen regeneration. (A) Masson staining and (B) Picrosirius red staining of the skin at the injection site of three kinds of PLA microsphere on Day 30. Type 1 collagen fibers are red or yellow, type 3 collagen fibers are green.